Overview: Provides fundamental understanding of the behavior of proteins at interfaces.Covers examples of protein interfacial activity in early development through product manufacture.Includes an overview of an. .Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often den
|