Overview: Autoimmune myasthenia gravis (MG) is a classical autoimmunedisease, for which the target antigen, nicotinic acetylcholinereceptor, has been cloned, sequenced and biochemically characterized.Antibodies to acetylcholine receptors destroy acetylcholine receptorat the neuromuscular junction, thus leading to defective neuromusculartransmission, muscle fatigue, and weakness. .In the last few years, rapid advances have been made in unraveling thecellular and molecular mechanisms involved in the pathogenesis of MG,both in the animal model, experimental autoimmune MG (EAMG), and inhuman MG. S
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