Titlebook: Metabolic Disorders and Critically Ill Patients; From Pathophysiology Carole Ichai,Hervé Quintard,Jean-Christophe Orban Book 2018 Springer

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Interpretation of Acid-Base Disordersaracterized by its capacity to release or conversely to consume them. This chapter will review most of the pathophysiological concepts of acid-base equilibrium and the mechanisms which are involved in its regulation. The history of the patient, the context, and clinical signs are essential to diagno

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Acidosis: Diagnosis and Treatmentt of an acidosis. Clinical signs of an acidosis are not specific, and the diagnosis is based on the context, on the history, and finally on the biological abnormalities. Metabolic acidosis (MA) must be distinguished from respiratory acidosis (RA) because causes and treatment are totally different. T

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Alkalosis: Diagnosis and Treatmentthe trouble, but its maintenance requires the presence of sustained factors. The classical Henderson-Hasselbalch theory is more and more replaced by the Stewart concept for interpreting metabolic alkalosis. The treatment of metabolic alkalosis is based on the simultaneous normalization of the genera

RAGE

Lactate: Metabolism, Pathophysiologyergetic condition. For a long time, hyperlactatemia was considered as toxic end waste, associated with lactic acidosis and tissue hypoxia-anaerobia. All these notions remain deeply anchored in our spirits but are frequently erroneous. Hyperlactatemia is really a good marker of poor outcome and a war