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Titlebook: Voltage-Sensitive Ion Channels; Biophysics of Molecu H. Richard Leuchtag Book 2008 Springer Science+Business Media B.V. 2008 animals.biolog

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书目名称Voltage-Sensitive Ion Channels
副标题Biophysics of Molecu
编辑H. Richard Leuchtag
视频video
概述Critically examines existing models of structure--function relations, guided by experimental data and physical principles.Unifies topics from electrophysiology, condensed-state physics, polymer chemis
图书封面Titlebook: Voltage-Sensitive Ion Channels; Biophysics of Molecu H. Richard Leuchtag Book 2008 Springer Science+Business Media B.V. 2008 animals.biolog
描述The goal of this book is to explore the complexity of a microscopic bit of matter that exists in a myriad of copies within our bodies, the voltage-sensitive ion channel. We seek to investigate the way in which these macromolecules make it possible for the long fibers of our nerve and muscle cells to conduct impulses. These integral components of cell membranes are marvels of nature‘s evolutionary adaptation. To understand them we must probe the boundaries of physics and chemistry. Since function is intimately related to structure, we examine the molecular structure of channels, focusing on physical principles that govern all matter. With the application of genetic methods, our knowledge of ion channels has broadened and deepened. In the hope that research can help ameliorate suffering, we discuss the diseases that arise from channel malfunctions due to genetic mutations. This book is intended for students and scientists who are willing to travel into uncharted waters of an interdisciplinary science. We approach the subject of volta- sensitive ion channels from various points of view. This book seeks to give voice to the viewpoints of the physical and the biological scientist, and t
出版日期Book 2008
关键词animals; biology; biophysics; chemistry; condensed matter; electrophysiology; information; organic chemistr
版次1
doihttps://doi.org/10.1007/978-1-4020-5525-6
isbn_softcover978-90-481-7384-6
isbn_ebook978-1-4020-5525-6
copyrightSpringer Science+Business Media B.V. 2008
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发表于 2025-3-21 22:55:16 | 显示全部楼层
Animal Electricity,ganisms in terms of physical laws. This book seeks to trace this endeavor in the area of voltage-sensitive ion channels. Like all subjects, electrophysiology has a history. In this chapter we will briefly review the early history of bioelectricity..The common view of science as an edifice that is bu
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Aspects Of Condensed Matter,eous media. To further our goal of explaining the behavior of the voltage-sensitive ion channels, we will review the physics of condensed materials with an eye to possible clues to the understanding of these channels. If we are to have a fair start in understanding their behavior in basic physical t
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Ions In The Electric Field, open question, particularly as long as the structure of voltage-sensitive ion channels is not fully understood. It is therefore worthwhile to acquaint ourselves with the movement of ions through materials that are well characterized. Let us step back a bit and recast this question more broadly: How
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Multi-Ion And Transient Electrodiffusion,w consider two complications: multi-ion electrodiffusion and time-dependent electrodiffusion. We will also note that the system of electrodiffusion equations obeys a set of scaling rules. We close this chapter with a critique of the classical electrodiffusion model as applied to membranes containing
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,What’s That Noise?,It was not until the development of the kinetic theory of gases in the latter part of the 19th Century that Brownian movement was found to be caused by thermal motions of the molecules in the liquid environment of the particles. The quantitative behavior of Brownian particles in thermal equilibrium
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Ion Channels, Proteins And Transitions,tage-sensitive ion conducting system is temperature-sensitive and has a heat-block temperature. Pulsing the temperature abruptly changes the membrane conductance. The membrane has significant optical properties, particularly birefringence. The membrane has significant electromechanical properties: I
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