| 书目名称 | Voltage Gated Sodium Channels |
| 编辑 | Peter C. Ruben |
| 视频video | |
| 概述 | Gives unprecedented insight into the structural basis of sodium channel function.Explores sodium channels from the perspectives of their biophysical behavior.Written by leading experts in the field.In |
| 丛书名称 | Handbook of Experimental Pharmacology |
| 图书封面 |  |
| 描述 | A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied. |
| 出版日期 | Book 2014 |
| 关键词 | channelopathies; drug binding; selectivity; structure/function relationships; toxins; voltage-dependent g |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-41588-3 |
| isbn_softcover | 978-3-662-51202-9 |
| isbn_ebook | 978-3-642-41588-3Series ISSN 0171-2004 Series E-ISSN 1865-0325 |
| issn_series | 0171-2004 |
| copyright | Springer-Verlag Berlin Heidelberg 2014 |
发表于 2025-3-21 17:57:37
