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Titlebook: Vitamin D; Basic and Clinical A Rajiv Kumar Book 1984 Martinus Nijhoff Publishing 1984 Vitamin D.kidney.leukemia.metabolism.osteoporosis.ph

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发表于 2025-3-21 18:45:18 | 显示全部楼层 |阅读模式
书目名称Vitamin D
副标题Basic and Clinical A
编辑Rajiv Kumar
视频video
图书封面Titlebook: Vitamin D; Basic and Clinical A Rajiv Kumar Book 1984 Martinus Nijhoff Publishing 1984 Vitamin D.kidney.leukemia.metabolism.osteoporosis.ph
描述Many advances in vitamin D physiology and biochemistry have been made in recent years. Vitamin D metabolites and analogs have found increasing application in clinical medicine. The purpose of this text is to review what is known about vitamin D physiology and draw attention to areas of vitamin D research that have changed within the last 2-3 years. Additionally, information concerning clinical aspects of vitamin D is also presented. More than 40 scientists have generously contributed chapters to this text; I thank them for their efforts. As might be expected, not everyone has the same point of view. Finally, I would like to acknowledge the secretarial and editorial efforts of Mrs. Cheryl Collins without whom this book would not have been completed. CONTRIBUTORS ETSUKO ABE, Department of Biochemistry, School of Dentistry, Showa University, 1-5-8, Hatanodai, Shinagawa-KU, Tokyo 142, Japan DAVID J. BAYLINK, Department of Medicine, Loma Linda University, Loma Linda, CA, and Pettis Veterans Hospital, 11201 Benton Street, Loma Linda, CA, 92357, USA NORMAN H. BELL, Department of Medicine, Medical University of South Carolina and Veterans Administration Medical Center, 109 Bee Street, Char
出版日期Book 1984
关键词Vitamin D; kidney; leukemia; metabolism; osteoporosis; physiology; steroids; diabetes
版次1
doihttps://doi.org/10.1007/978-1-4613-2839-1
isbn_softcover978-1-4612-9793-2
isbn_ebook978-1-4613-2839-1
copyrightMartinus Nijhoff Publishing 1984
The information of publication is updating

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Vitamin D Metabolism the processes that regulate its production. Much less attention has been directed to the other metabolites of 25-OH-D., and most of that has concerned 24.,25-(OH).D., a compound whose function is controversial. The complex metabolism of 25-OH-D., other than 1α-hydroxylation, may be a degradative me
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1,25-Dihydroxyvitamin D: Response to and Production by Bone Cellsffecting the intestinal absorption and the skeletal resorption of these minerals. The following discussion will focus on the mechanisms by which 1,25-diOHD affects endosteal bone formation and endosteal bone resorption to mediate the net release of calcium and phosphate from the endosteal bone miner
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Mammalian 25-Hydroxyvitamin D-1α-Hydroxylase: Measurement and Regulationnsertion of a hydroxyl function at the 1α-position of 25- hydroxyvitamin D (25-OH-D). 1α-Hydroxylase has been intensively studied in birds and there are several excellent reviews (1–3). Until the recent development of . . assays allowed direct measurement of 1α-hydroxylase activity, the properties o
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Vitamin D Metabolism During Pregnancyand the dietary intake of vitamin D (1). The serum concentration of 25-OHD is regarded as a measure of the vitamin D status in the absence of intestinal or hepatic disease. A dietary deficiency of vitamin D or a limited exposure of the skin to sunlight would be associated with a low serum level of 2
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Calcium Absorption and the Molecular Effects OF Vitamin D3in this process (cf. ref. 1 for earlier review). Physiological studies had demonstrated that vitamin D affected, directly or indirectly, at least two processes in the transfer of Ca. from intestinal lumen through the intestinal cell to the lamina propria (1,2). One process is the movement of Ca. int
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Mode of Action of 1α,25-Dihydroxyvitamin Djor circulating form, 25-OH-D., serves as a precursor for the production of 1,25(OH).D. or 24R,25(OH).D. in the kidney. Recent studies from our laboratory show that these two active forms of the vitamin can be further metabolized in the mammalian kidney. The metabolism of 24R,25(OH).D. leads through
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