书目名称 | Viruses, Genes, and Cancer | 编辑 | Eric Hunter,Klaus Bister | 视频video | | 概述 | Includes a foreword by the Nobel laureates J. Michael Bishop and Harold Varmus.Casts new light on the role of viruses and genes in the etiology of human cancer.Discusses the latest developments in HIV | 丛书名称 | Current Topics in Microbiology and Immunology | 图书封面 |  | 描述 | .This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.. | 出版日期 | Book 2017 | 关键词 | Virus-host cell interactions; Oncogenic signaling; MYC; RAF; PI3 kinase; mTOR; MicroRNA; Tumor suppressors; | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-61804-3 | isbn_softcover | 978-3-319-87167-7 | isbn_ebook | 978-3-319-61804-3Series ISSN 0070-217X Series E-ISSN 2196-9965 | issn_series | 0070-217X | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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