Titlebook: Viruses in Human Gene Therapy; Jean-Michel H. Vos Book 1995 Jean-Michel H. Vos 1995 biology.gene.gene therapy.gene transfer.genes.genetics

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Adenovirus-mediated In Vivo Gene Therapy, place in gastrointestinal, respiratory, or ocular epithelial cells, resulting in pathological alterations mediated by direct tissue damage. For example, some serotypes (Ad 3, 20) are associated with “swimming pool conjunctivitis” or gastroenteritis (Ad40), while Ad5 is responsible for respiratory i

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Adeno-associated Viral Vectors,for gene therapy purposes. At present, recombinant retrovirus stock can only be made to low titers. While the retrovirus vectors can infect a broad class of cell types, cell replication and DNA synthesis are required for provirus integration, restricting their efficient use to replicating cells.

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Glucocorticoids

Poxviruses as Genetic Vectors,y of poxviruses, with emphasis on those aspects important in using poxviruses as expression vectors. (Cited references are meant to be illustrative but not comprehensive. For more indepth coverage, the reader is directed to the following reviews: Fenner, Wittek and Dumbell 1989; Moss 1990a; Buller a

Fermentation

constellation

Hepatitis Delta Virus,lta virus (HDV) to deliver small RNA sequences with potential therapeutic activity. Both the advantages and disadvantages of HDV are considered, with special emphasis on the use of modified HDV for the treatment of chronic hepatitis B virus (HBV) infections.

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Adeno-associated Viral Vectors,into mammalian cells. Viral expression vectors, reviewed by Rigby (1983) have been developed using DNA viruses, such as papova (i.e., SV40), adeno, herpes, and pox viruses and RNA viruses, such as retrovirus. Recently, the most commonly used model vectors have been derived from murine and avian retr

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Recessive

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