Titlebook: Viral Genome Replication; Kevin D. Raney,Matthias Gotte,Craig E.‘Cameron Book 2009 Springer-Verlag US 2009 DNA.HIV.RNA.Viruses.enzymes.inf

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Hepatitis C Virus Genome Replicationof viral and host factors in this process. Where applicable, we will draw comparisons to other viruses within this volume. Nevertheless, due to space limitations this review is not meant to be comprehensive, and we apologize in advance to authors whose work could not be cited.

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Hepadnaviral Genomic Replicationic, establish chronic infections, follow the same replication cycle, and have nearly identical genetic organizations. The hepadnaviral genomic replication mechanism has been investigated primarily with HBV and Duck Hepatitis B virus (DHBV).

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Flaviviruseslular membranes induced by viral infection. The viral RNA is not just a passive template; it plays an active role acquiring dynamic tertiary structures during viral replication. RNA synthesis is regulated by .-acting elements present at the 5′- and 3′-ends of the viral genome. These elements include

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Hepatitis C Virus Genome Replicationatocellular carcinoma (Alter and Seeff 2000). The success of this virus is largely due to its ability to cause persistent infections – often lasting for decades – in over 70% of infected individuals. Thus, HCV infection leads to a dynamic interplay between viral replication, host antiviral responses

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Brome Mosaic Virus RNA Replication and Transcriptionied in the laboratory. The impact of BMV, however, is not so much as a plant pathogen, but as a model for in-depth studies of the infection process of positive-stranded RNA viruses. As such, BMV is responsible for several firsts. (1) BMV was among the first to be translated using a cell-free system

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Retrovirusesding from the infected cell. The lipid bilayer therefore contains cellular proteins as well as the viral envelope glycoproteins. These glycoproteins are constituted by a transmembrane subunit (TM) associated to the surface protein (SU), present on the virion. Underneath the membrane is a spherical s