Titlebook: Vascular Mechanobiology in Physiology and Disease; Markus Hecker,Dirk J. Duncker Book 2021 Springer Nature Switzerland AG 2021 mechanobiol

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Parnaz Boodagh,Zewei Tao,Sean P. Keyser,Wei Tant of PEG in the presence of salt (NaCl) is also alleviated by proline. The precipitation of the radioimmune complex by PEG is diminished by proline and by a mixture of free amino acids..These results indicate the generality of the three-way interaction between proline, protein and PEG. They may be o

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2509-7830 series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering..978-3-030-63166-6978-3-030-63164-2Series ISSN 2509-7830 Series E-ISSN 2509-7849

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GPCRs Under Flow and Pressure,ular smooth muscle cells mediating myogenic vasoconstriction. Seven GPCRs are currently discussed as potential mechanosensors in blood vessels. However, a principal molecular mechanism underlying mechanically induced GPCR activation remained largely elusive. Recent findings suggest that at the molec

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Mechanobiology of Arterial Hypertension,ownstream capillary pressure stable, in the face of an increased pressure head. In this light, adaptive responses that decrease luminal diameter to control wall stress appear as maladaptive and energy-consuming. In large arteries, wall thickening is also observed in hypertension. However, the main i

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Hemodynamics and Vascular Remodeling,ile the endothelial lining of vessels experiences shear stresses as a consequence of blood’s motion over it. Both types of stress can elicit biological responses from cells in the walls, including growth and remodeling that are required for the normal function of the vasculature, and the development

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New Kids on the Block: The Emerging Role of YAP/TAZ in Vascular Cell Mechanotransduction,d organ size control. YAP and TAZ are exquisitely sensitive to mechanical cues, such as substrate stiffness and shear stress, and the realization is growing that they play roles in arterial remodeling and aneurysm formation. This chapter discusses how YAP and TAZ are activated by mechanical cues, th