Titlebook: Vascular Ion Channels in Physiology and Disease; Irena Levitan, PhD,Alex M. Dopico, MD, PhD Book 2016 Springer International Publishing Sw

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Irena Levitan, PhD,Alex M. Dopico, MD, PhDPresents the studies undertaken in the last decade to elucidate the roles of ion channels in different vascular diseases.Focuses on the roles of ion channels in vascular tissues under normal and patho

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978-3-319-80613-6Springer International Publishing Switzerland 2016

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https://doi.org/10.1007/978-3-319-29635-7ion channels; proteins; transport; endothelium; calcium ions; potassium

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Lysosomal Transient Receptor Potential Mucolipin (TRPML) Channels in Vascular Regulation and Diseaseothelin 1 (ET-1), reactive oxidative species (ROS), and death receptor ligand (FasL). The defects or derangement of the lysosomal TRPMLl channel activity have been implicated in vascular injury or diseases such as endothelial dysfunction, apoptosis and even atherosclerosis.

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