| 书目名称 | Vascular Endothelium | | 副标题 | Receptors and Transd | | 编辑 | John D. Catravas,C. Norman Gillis,Una S. Ryan | | 视频video | | | 丛书名称 | NATO Science Series B: | | 图书封面 |  | | 描述 | Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now firmly established as active and essential participants in a host of crucial physiological and pathophysiological functions. Probably the two most important factors responsible for promoting the current knowledge of endothelial functions are 1) observations in the late sixties-early seventies that many non-ventilatory properties of the lung could be attributed to the pulmonary endothelium and 2) the establishment, in the early and mid-seventies of procedures for routine culture of vascular endothelial cells. Many of these endothelial functions require the presence of receptors on the surface of the plasma membrane. There is now evidence for the existence among others of muscarinic, a-and /3-adrenergic, purine, insulin, histamine, bradykinin, lipoprotein, thrombin, paf, fibronectin, vitronectin, interleukin and albumin receptors. For some of these ligands, there is evidence only for the existence of endothelial binding sites. Traditionally, agonist binding must elicit a response for the binding site to be considered a receptor and, in some cases, the nature of the response resulting f | | 出版日期 | Book 1989 | | 关键词 | Calcium; Plasma; Purine; cell membrane; cells; cytokine; endothelium; lipoprotein; pharmacology; phosphorylat | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-8532-5 | | isbn_softcover | 978-1-4684-8534-9 | | isbn_ebook | 978-1-4684-8532-5Series ISSN 0258-1221 | | issn_series | 0258-1221 | | copyright | Plenum Press, New York 1989 |
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发表于 2025-3-21 18:25:00
