Titlebook: Value Creation for a Sustainable World; Innovating for Ecolo Laszlo Zsolnai,Thomas Walker,Paul Shrivastava Book 2023 The Editor(s) (if appl

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Ove Jakobsen,Fritjof Caprae uterine cervix. It is more than 70 years since Hans Hínselmann reported the possibility of looking at the surface of the ectocervix under magnification. Those creative observations led to the development of cervical cytology and colposcopy. The development of both ideas created the base for the ea

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David Donoghue,Eleanor O’ Higginshe systems require further attention. Present vectors vary widely in efficacy of DNA transfer, and parameters important in regulating this process need to be more clearly defined. Following establishment of a generalised prototype, modifications could then be made to target specifically to tumours,

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Jacob Dahl Rendtorffalignancies, leading to oncogenic activation either by the formation of chimeric transforming genes or by deregulation of transcription (Croce, 1987; Rabbitts, 1994). Gene fusion is observed in the majority of the myeloid tumors and in soft tissue sarcomas, and less frequently in B and T cell leukem

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Knut Ims,Laszlo Zsolnaitem. This has been shown not only in experimental animals but also for spontaneously arising human tumours. Tumour progression may therefore require the evolution of variants which can “escape” the immune response. Mechanisms for the escape of tumours from immune responses (endogenous or therapeutic

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Zoltan Rozsafferent focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up­ dated summaries in various areas of classical tumor immunology: specific ant

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Jozsef Veressresults of this process are usually extremely helpful to the clinician who is responsible for planning further investigations and therapy. And for a long time the pathologist has worked with his microscope, eyes and brain — now and then turning to the laboratory for special stains to enlighten the p