| 书目名称 | Vaccines for Pandemic Influenza | | 编辑 | Richard W. Compans,Walter A. Orenstein | | 视频video | | | 丛书名称 | Current Topics in Microbiology and Immunology | | 图书封面 |  | | 描述 | Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential bio | | 出版日期 | Book 2009 | | 关键词 | Antigen; DNA vaccines; H5N1 viruses; NS1 proteins; Radiologieinformationssystem; attenuated vaccines; avia | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-540-92165-3 | | isbn_softcover | 978-3-642-24240-3 | | isbn_ebook | 978-3-540-92165-3Series ISSN 0070-217X Series E-ISSN 2196-9965 | | issn_series | 0070-217X | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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发表于 2025-3-21 19:08:01
