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Titlebook: Vaccine Adjuvants; Methods and Protocol Gwyn Davies Book 2010 Humana Press 2010 AS04 adjuvant.Aluminium salts.Antigen.Antigens.Cytokines.Im

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Thomas Lindenstrøm,Peter Andersen,Else Marie Agger, Veränderungen der Psychomotorik, affektive Störungen, sexuelle Störungen, Störungen der Impulskontrolle. Eßstörungen sind häufige Erkrankungen, nehmen häufig einen subchronischen oder chronischen Verlauf und können zu einem hohen Ausmaß an psychosozialer Beeinträchtigung führen. Die wissenschaftli
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Immunology of Vaccine Adjuvants,echanisms of action. They are categorized functionally in two major groups as facilitators of signal 1 and/or signal 2. The mode(s) of action of some well-known adjuvant prototypes is discussed in the context of this classification.
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Preclinical Development of AS04,rmulations. Preclinical evaluation demonstrated the relevance of using AS04 in situations where high and long-lasting antibody levels are needed. This represents the basis for the successful application of AS04 in vaccines against hepatitis B virus and human papillomavirus.
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Nonclinical Safety Assessment of Vaccines and Adjuvants,me cases, eliminates candidates that have unacceptable risks for human testing. This review summarizes the requirements for the nonclinical testing of vaccines and adjuvants needed in support of all phases of human clinical trials.
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NKT Cell Responses to Glycolipid Activation,stimulation by α-GalCer, including production of high levels of immune-regulatory cytokines and bystander activation of several cell types including NK, B, T, and dendritic cells. Both in vitro and in vivo methods have been developed for the study of NKT responses to glycolipid presentation by CD1d.
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Tracking Dendritic Cells In Vivo,actions dynamically in vivo. Here we describe some of the immunological and microscopical techniques that have enabled the analysis of the immune cells and their interactions, in vivo, in real time. It is only by performing such detailed and fundamental studies in vivo that we can fully understand t
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Determining Adjuvant Activity on T-Cell Function In Vivo: Th Cells,ch a development and selection process is to determine the adjuvant activity on T-cell function in vivo. Expanding our knowledge on these mechanisms will improve our chance of developing new successful vaccines designed to target specific diseases.
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