| 书目名称 | Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants | | 编辑 | Curtis C. Travis | | 视频video | | | 丛书名称 | NATO Science Series A: | | 图书封面 |  | | 描述 | Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can al | | 出版日期 | Book 1993 | | 关键词 | Mutation; ecosystems; production; toxicity; toxicology; ecotoxicology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4899-2052-2 | | isbn_softcover | 978-1-4899-2054-6 | | isbn_ebook | 978-1-4899-2052-2 | | copyright | Springer Science+Business Media New York 1993 |
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发表于 2025-3-21 20:05:55
