Titlebook: Urine; Promising Biomarker Youhe Gao Book 2019 Springer Nature Singapore Pte Ltd. 2019 Urine.Biomarker.Early diagnosis.Animal models.Cance

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Urine Is Not a Human Waste but a Medical Treasureled by homeostatic mechanisms of the body, all cell bathing in body fluids, mainly blood and cerebral spinal fluid, tend to remove early changes. Wastes of the body, such as urine and breath, accumulating all kinds of early changes, are better biomarker sources.

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Human Urine Proteome: A Powerful Source for Clinical Researchhers endeavored in profiling urinary proteome and discovering potential disease biomarkers. However, there are still many challenges in the studies of urinary proteome due to the complexity of urine. In this article, we review current status of urinary sample preparation, including collection, stora

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Comparison of Urinary Proteomes Among Three Animal Modelscan reflect multiple changes in the body. Animal models can simulate human disease processes, monitor disease changes, and provide clues for early diagnosis. In this chapter, clues are provided for the dominant model animals associated with disease selection by comparing the urine proteome of rats,

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Application of Peptide Level and Posttranslational Modifications to Integrative Analyses in Proteomifrom the peptide information. At the same time, posttranslational modifications also play an important role in peptide matching. However, the protein inference step can produce errors and a loss of information. In addition, the genes and proteins are highly homologous in some species, such as human

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Urinary Protein Biomarker Database 2.0: A Literature-Curated Database for Protein Biomarkers in Urind control samples in a single experiment; however, selection of promise biomarker candidates for further validation study remains difficult. UPBD (Urinary Protein Biomarker Database) was established to collect information of urinary biomarkers or biomarker candidates from published literature in 201

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Urine Glucose Levels Are Disordered Before Blood Glucose Level Increase Was Observed in Zucker Diabe period of incubation of the disease. Pre-diabetes is an early warning signal of diabetes, and the change of urine glucose in this period has been ignored even though urine has long been related with diabetes. In this study, Zucker diabetic fatty (ZDF) rats were used to test if there were changes in