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Titlebook: Upscaling of Bio-Nano-Processes; Selective Bioseparat Hermann Nirschl,Karsten Keller Book 2014 Springer-Verlag Berlin Heidelberg 2014 Biopr

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Magnetically Enhanced Centrifugation for Industrial Useial for industrial use. Magnetic particles are separated to a wire filter, from which they are cleaned by centrifugal forces to the chamber wall. The simulation of magnetic particles collected by a wire were possible by the discrete element method. The simulation shows the detachment of particles fr
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Continuous Magnetic Extraction for Protein Purificationional surface groups, e.g., ion exchange ligands, serve as carriers for the target protein. Together with a mixture of thermoresponsive surfactants and binding buffer these carriers are added to the feed containing the target protein. After binding the target within minutes, the mixture is heated ab
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Conclusionerent elements: the . of coated particles with magnetic core, a selective . which needs to be adapted to adsorb the target matter and exclude contamination, the ., which need to fit for the process in scale, budget and separation characteristics, and the . All of these elements need to fit together
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Introduction,echnology, from systems biology to bioreactor technology, have made large-scale production of sophisticated new biomolecular materials possible. However, the costs of producing these exciting new materials can be prohibitive due to separation processing, which typically constitute 80 % of the total cost of production.
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Book 2014magnetic nanoparticles and a novel technology for the upscaling of protein separation. The results come from the EU Project "MagPro2Life", which was conducted in cooperation of several european institutions and companies. .
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