| 书目名称 | Untranslated Gene Regions and Other Non-coding Elements |
| 副标题 | Regulation of Eukary |
| 编辑 | Lucy W. Barrett,Sue Fletcher,Steve D. Wilton |
| 视频video | |
| 概述 | Revisits the idea of "junk" genetic material.Easy to read, concise overview of a complex subject.Includes supplementary material: |
| 丛书名称 | SpringerBriefs in Biochemistry and Molecular Biology |
| 图书封面 |  |
| 描述 | There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. |
| 出版日期 | Book 2013 |
| 关键词 | DNA regulation; Gene expression; Introns; Junk DNA; Non-coding RNA; Promotors |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-0348-0679-4 |
| isbn_softcover | 978-3-0348-0678-7 |
| isbn_ebook | 978-3-0348-0679-4Series ISSN 2211-9353 Series E-ISSN 2211-9361 |
| issn_series | 2211-9353 |
| copyright | The Author(s) 2013 |
发表于 2025-3-21 16:07:28
