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Titlebook: Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection; Vishwanath Venketaraman Book 2018 Springer Nature Swi

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书目名称Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection
编辑Vishwanath Venketaraman
视频video
概述Editor and contributors are internationally recognized experts in TB research.Discusses the latest findings on comorbidity between TB and various conditions.Novel focus on the effects of chronic smoki
图书封面Titlebook: Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection;  Vishwanath Venketaraman Book 2018 Springer Nature Swi
描述.According to the World Health Organization, approximately one third of the world’s population is latently infected with .Mycobacterium tuberculosis (M. tb. [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and .M. tb. co-infection. ..TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition. ..This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host’s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smokingand aging, and strategies to restore favorable immune responses against this deadly pathogen..
出版日期Book 2018
关键词HIV infected individuals; chronic smokers; diabetes; tuberculosis; mycobacterium; extrapulmonary; pulmonar
版次1
doihttps://doi.org/10.1007/978-3-319-97367-8
isbn_softcover978-3-030-07344-2
isbn_ebook978-3-319-97367-8
copyrightSpringer Nature Switzerland AG 2018
The information of publication is updating

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Diabetes and Tuberculosis,rperforming response by monocytes and macrophages. These defects provide a critical early opportunity for favorable replication of . within the diabetic alveolar macrophages. Eventual but delayed T-cell priming does occur, and in TB patients, this T-cell response is exaggerated, perhaps as a reflect
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Recent Advances in Tuberculosis Immunodiagnostics,er not sensitive or efficient enough to help diagnose large numbers of TB patients that live in high-burden TB endemic countries. New, blood based immunodiagnostic approaches that can help diagnose not only PTB but also EPTB and PEDTB are critically needed.
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Animal Models of Tuberculosis,zebrafish to nonhuman primates, have been explored to understand the pathophysiology of acute/chronic active TB, LTBI, and reactivation. Knowledge gained from such studies can aid in developing more effective intervention strategies to combat TB in humans. In this chapter, we discuss the salient fea
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odel in an attempt to aid researchers and marketers doing business in the online platforms to strategize their move considering the innovations and amendments essential for delivering the best service experience to its key stakeholders. Furthermore, the relevance of the e-servicescape model in the c
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