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Titlebook: Unconventional Agents and Unclassified Viruses; Recent Advances in B O.-R. Kaaden,W. Eichhorn,C.-P. Czerny Conference proceedings 1993 Spri

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Serological and antigenical findings indicating pestivirus in manh radioimmuno-precipitation assays and IIF-flow cytometry. A doublet of 120 kD was identified only in cell lysates, indicating a non-structural protein. In order to rule out cross reactivity 30 sera from Hepatitis C seropositive patients were tested against the isolate by IIF-flow cytometry. No anti
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Molecular biology and evolution of filovirusesonary lineage for all these viruses. Sequence analyses of single genes, however, showed that filoviruses are more closely related to paramyxoviruses, particularly human respiratory syncytial virus. These data support the concept of the taxonomic order . for all nonsegmented negative-strand RNA virus
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Biology and neurobiology of Borna disease viruses (BDV), defined by antibodies, neutralizability andponents of the soluble antigen (60, 40/38, 25 and 14.5 kD proteins). Analysis of the s-antigen complex with these sera and 6 stable monoclonal antibodies revealed that it consists of 40/38 and 25 kD proteins. Although each of these antibodies detected intracellular virus-specific structures they did
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Pathogenesis of Borna diseasenot caused by the infecting virus itself but rather by the hosts immune response towards it, i.e. by a virus-induced cell-mediated immunopathological reaction. The importance of virus-specific CD4+ T cells as exemplified by a cultured T cell line and of CD8+ T cells as shown by immunomodulatory subs
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Borna Disease virus infection and affective disorders in manpatients with different psychiatric diagnosis, the highest proportion of antibody carriers was detected among patients with major depression (more than 30%), compared to only 8% among patients with dysthymia (neurotic depression). This led us to hypothesize that Bornavirus infection might contribute
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