Titlebook: Ubiquitin-Proteasome Protocols; Cam Patterson,Douglas M. Cyr Book 2005 Humana Press 2005 Endoplasmatisches Reticulum.Termination.biochemis

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Purification of E1 and E1-Like Enzymesman red blood cells in yields (2–4 nmol/U of blood) that make this an attractive alternative to expression of the proteolytically labile recombinant protein. In addition, two stoichiometric activity assays are described that rely on formation of the E1 .I-ubiquitin thiol ester and ubiquitin [2,8-.H]adenylate intermediates.

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Shahri Raasi,Cecile M. Pickarto effective prevention. This has always been one of our worst kept secrets. Equally conflicts of interest [.] assume particular relevance in an occupation whose foundation values demand a robust ethical identity. This is the topic of this essay.

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Small-Molecule Inhibitors of Proteasome Activityl-molecule compounds blocking its activities. Besides being candidates for drugs against cancer, autoimmune diseases, inflammation, or stroke, specific proteasome inhibitors are indispensable tools for biochemical and cell biology investigations of the proteasome and proteasome-ubiquitin system. Num