书目名称 | Ubiquitin Family Modifiers and the Proteasome |
副标题 | Reviews and Protocol |
编辑 | R. Jürgen Dohmen,Martin Scheffner |
视频video | |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .The ubiquitin-proteasome system (UPS) and ubiquitin-related modifiers are not only involved in cellular protein quality control but also in the regulation of many fundamental cellular processes/pathways as well as in their disease-relevant aberrations. .Ubiquitin Family Modifiers and Proteasome: Reviews and Protocols. presents both novel developments in UPS research and important methods related to the main recent advances in the field of ubiquitin family modifiers. Divided into five convenient sections, this volume focuses on the enzymology and substrate identification of ubiquitin family modifiers, the recognition and chain formation of these modifiers, the analysis of proteasome biogenesis and function, protein quality control, and finally the use of small molecules and strategies to study or manipulate the function of the UPS and of ubiquitin family modifiers, respectively. Written in the highly successful .Methods in Molecular Biology™. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.. .Authoritative an |
出版日期 | Book 2012 |
关键词 | UbF modifiers; Ubiquitin-Proteasome system function; Ubiquitin-related modifiers; cellular ubiquitylati |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-61779-474-2 |
isbn_softcover | 978-1-4939-5905-1 |
isbn_ebook | 978-1-61779-474-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media, LLC 2012 |