| 书目名称 | Two Faces of Evil: Cancer and Neurodegeneration |
| 编辑 | Thomas Curran,Yves Christen |
| 视频video | |
| 概述 | Several new concepts were shared that will stimulate future research and perhaps contribute to better therapies for cancer patients as well as those struggling with the ravages of neurodegeneration..I |
| 丛书名称 | Research and Perspectives in Alzheimer‘s Disease |
| 图书封面 |  |
| 描述 | Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profound tolls on humanity and they have been subject to a great deal of research designed to ameliorate this suffering. For the most part, the topics have been viewed as distinct and rarely do opportunities arise for transdisciplinary discussions among experts in both fields. However, cancer and neurodegeneration represent .yin-yang. counterpoints in the regulation of cell growth, and it is reasonable to hypothesize that key regulatory events mediated by oncogenes and tumor suppressor genes in cancer may also affect neurodegenerative processes |
| 出版日期 | Book 2011 |
| 关键词 | Cdk2; Cdk4; Cdk5; DNA repair pathway; Ube3A; hedgehog signaling pathway; long-term memory storage; medullob |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-16602-0 |
| isbn_softcover | 978-3-642-26771-0 |
| isbn_ebook | 978-3-642-16602-0Series ISSN 0945-6066 Series E-ISSN 2196-310X |
| issn_series | 0945-6066 |
| copyright | Springer-Verlag Berlin Heidelberg 2011 |
发表于 2025-3-21 17:05:36
