| 书目名称 | Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation |
| 编辑 | Annika B. Malmberg,Keith R. Bley |
| 视频video | |
| 概述 | First comprehensive volume on this timely topic.Discusses the therapeutic potential of TRPV1.Written by well-known scientists in the field.Includes supplementary material: |
| 丛书名称 | Progress in Inflammation Research |
| 图书封面 |  |
| 描述 | Despite tremendous advances in the understanding of the sensory nervous system which have accompanied the recent explosive growth of the neurosciences, rema- ably few innovative medicines directed towards pain and inflammation are ava- able. Indeed, many patients are still prescribed analgesic and anti-inflammatory medications that were identified long ago as components of herbal remedies. Si- larly, potential new medicines in clinical evaluation based on capsaicin and the c- saicin receptor are both grounded firmly on folk traditions and yet rely upon the most contemporary techniques of drug discovery and delivery. The first formal report of the pain-relieving properties of capsaicin appeared in 1850 [1]. However, for centuries before this, capsaicin-containing extracts had been used as folk medicines in cultures with access to pepper plants, much in the same way as poppy or willow-bark extracts were. Despite widespread use, it was not until 1878 that the selective action of capsaicin on the sensory nervous system was r- ognized [2]. In Chapter 1 of this volume, Janos Szolcsányi reviews this early research, which culminated with the seminal studies of Nicholas Jansco and his c- le |
| 出版日期 | Book 2005 |
| 关键词 | Activation; analgesics; cannabinoid; diseases; drug; drug development; inflammation; lead; muscle; neurons; pa |
| 版次 | 1 |
| doi | https://doi.org/10.1007/3-7643-7379-2 |
| isbn_ebook | 978-3-7643-7379-5Series ISSN 1422-7746 Series E-ISSN 2296-4525 |
| issn_series | 1422-7746 |
| copyright | Birkhäuser Basel 2005 |
发表于 2025-3-21 18:31:44
