| 书目名称 | Transposons and the Dynamic Genome |
| 编辑 | Dirk-Henner Lankenau,Jean-Nicolas Volff |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Genome Dynamics and Stability |
| 图书封面 |  |
| 描述 | .There are only few major key functions that lie beneath the fundamental architecture of metabolism and life. These are multiplication, variation and heredity. Only if these factors interact synergistically can Darwinian selection power the evolution of biodiversity. Transposable elements have always played a major role in this process. The genomes of all organisms consist of chromosomes that are built up of double-stranded nucleic acid chains on whose stability and integrity the existence of cells depend. While DNA repair warrants the chemical integrity of DNA and protects it from metabolic and environmental mutagens, meiotic recombination and transposable element activity appear to counteract the molecular guardians of genome stability. Transposable elements and their kind often make up the bulk of genomic DNA, often approaching 50% of the genome. By contrast, the classic genes represent as little as 1.8% of genomic DNA, in case of the human genome. ...This volume gives an overview on mobile DNA and how such contradiction to the obligatory stability of genomes can be understood. Obviously, an understanding can only be achieved by cutting deeply into the evolutionary history of li |
| 出版日期 | Book 2009 |
| 关键词 | Activation; Chromosom; DNA; RNA; chromosome; evolution; genes; metabolism; recombination; regulation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-02005-6 |
| isbn_softcover | 978-3-642-24252-6 |
| isbn_ebook | 978-3-642-02005-6Series ISSN 1861-3373 Series E-ISSN 1861-3381 |
| issn_series | 1861-3373 |
| copyright | Springer-Verlag Berlin Heidelberg 2009 |
发表于 2025-3-21 18:28:12
