| 书目名称 | Translational Pancreatic Cancer Research |
| 副标题 | From Understanding o |
| 编辑 | Christoph W. Michalski,Jonas Rosendahl,Jörg Kleeff |
| 视频video | |
| 概述 | Presents how research results can be translated into clinical trials..Incorporates a multi-disciplinary approach..Written by experts in the field. |
| 丛书名称 | Molecular and Translational Medicine |
| 图书封面 |  |
| 描述 | This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer and stromal, epigenetic and metabolism targeting as promising approaches to be translated into early phase clinical trials. Chapters within this part also deal with approaches that are close to being implemented in clinical practice or are already being tested in (early) clinical trials, such asthose that targeting the immune systems and strategies to overcome immunotherapy resistance; phase 1 clinical trials and translational approaches in surgical treatment. .Written by experts in their fields, |
| 出版日期 | Book 2020 |
| 关键词 | PDAC PRECURSORS; BIOMARKERS AND STRATIFICATION; PERSONALIZED TREATMENT; Epigenetic targeting; Molecular |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-49476-6 |
| isbn_softcover | 978-3-030-49478-0 |
| isbn_ebook | 978-3-030-49476-6Series ISSN 2197-7852 Series E-ISSN 2197-7860 |
| issn_series | 2197-7852 |
| copyright | Springer Nature Switzerland AG 2020 |
发表于 2025-3-21 17:19:16
