| 书目名称 | Transcriptional and Translational Regulation of Stem Cells |
| 编辑 | Gary Hime,Helen Abud |
| 视频video | |
| 概述 | Latest research in stem cell regulation.Stem cells from various species are discussed providing a unique overview of stem cell biology.The regulators of stem cells provide new candidates for disease t |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations. |
| 出版日期 | Book 2013 |
| 关键词 | epigenetic; microRNAs; stem cells; transcription; translation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-6621-1 |
| isbn_softcover | 978-94-024-0182-0 |
| isbn_ebook | 978-94-007-6621-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 201 |
发表于 2025-3-21 20:02:56
