| 书目名称 | Thyroid Hormone Disruption and Neurodevelopment |
| 编辑 | Noriyuki Koibuchi,Paul M. Yen |
| 视频video | |
| 概述 | The first book to describe the effects of thyroid hormone disruptions on neurodevelopment.Provides perspectives from molecular studies, animal studies, and human studies.Suitable for both basic resear |
| 丛书名称 | Contemporary Clinical Neuroscience |
| 图书封面 |  |
| 描述 | Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, w |
| 出版日期 | Book 2016 |
| 关键词 | brain development; gene mutation; hypothyroidism; iodine; thyroid hormone |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-3737-0 |
| isbn_softcover | 978-1-4939-8124-3 |
| isbn_ebook | 978-1-4939-3737-0Series ISSN 2627-535X Series E-ISSN 2627-5341 |
| issn_series | 2627-535X |
| copyright | Springer Science+Business Media New York 2016 |
发表于 2025-3-21 16:43:26
