书目名称 | The Long and Short Non-coding RNAs in Cancer Biology |
编辑 | Erwei Song |
视频video | |
概述 | Provides a comprehensive knowledge of long and short ncRNAs.Chapters highlight recent advances in specific topics, like the molecular mechanisms of various classes of ncRNAs in cancer.Contributed by e |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets. . . . |
出版日期 | Book 2016 |
关键词 | Cancer Biology; Diagnostic Biomarkers; Long non-coding RNAs; MicroRNA; Therapeutic targets; cancer diagno |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-10-1498-7 |
isbn_softcover | 978-981-10-9367-8 |
isbn_ebook | 978-981-10-1498-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |