| 书目名称 | The Immunogenetics of Dermatologic Diseases |
| 编辑 | Nima Rezaei,Fateme Rajabi |
| 视频video | |
| 概述 | Offers a unique perspective on the pathogenesis and immunological dynamic of dermatological conditions.Intends to gather information on the functional significance of data provided by genome-wide asso |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies..Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might h |
| 出版日期 | Book 2022 |
| 关键词 | dermatology; auto-immunity; gene polymorphisms; single nucleotide variants; psoriases; melanoma; skin canc |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-92616-8 |
| isbn_softcover | 978-3-030-92618-2 |
| isbn_ebook | 978-3-030-92616-8Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:26:40
