| 书目名称 | The Calabar Bean and its Alkaloids | | 副标题 | From Magic, via Mira | | 编辑 | Brian Robinson | | 视频video | | | 概述 | One of the most exciting and interesting aspects of the study of natural products is the “field work” involving ethnological and ethnobotanical studies and which, where apposite, have been alluded to | | 图书封面 |  | | 描述 | .Investigations into Calabar beans (the dried ripe seeds of .Physostigma venenosum.) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, .l.-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound”) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial.. | | 出版日期 | Book 2023 | | 关键词 | Alkaloids; Structure Elucidation; Synthesis; Pharmacology; Experimental Therapeutics | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-024-1191-1 | | isbn_ebook | 978-94-024-1191-1 | | copyright | Springer Nature B.V. 2023 |
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发表于 2025-3-21 17:00:55
