| 书目名称 | Target Discovery and Validation Reviews and Protocols | | 副标题 | Emerging Molecular T | | 编辑 | Mouldy Sioud | | 视频video | | | 概述 | Includes supplementary material: | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Target Discovery and Validation Reviews and Protocols, Volumes 1 and 2 review the most progressive and current methods for drug target discovery and validation. These volumes explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders...Volume 1 focuses on novel and innovative techniques, and presents the most up-to-date protocols available for maximizing the likelihood of achieving target-selective inhibition in vivo while minimizing side effects. The profound impact of genomics, proteomics and bioinformatics on target discovery is explored, and specific attention is given to the role of transgenic and knockout animals in functional genomics and target validation. Cancer researchers will find tremendous value in the molecular classification of breast cancers and the review of protocols for tumor antigens and cancer vaccines. The methods and protocols collected here, all reviewed by leading scientists and clinicians, present the practical details necessary for translating the enormous discovery potential of the genome into | | 出版日期 | Book 2007 | | 关键词 | DNA; Proteomics; Translation; bioinformatics; classification; gene expression; molecular mechanisms | | 版次 | 1 | | doi | https://doi.org/10.1385/1597452084 | | isbn_softcover | 978-1-61737-827-0 | | isbn_ebook | 978-1-59745-208-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2007 |
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发表于 2025-3-21 18:53:28
