书目名称 | Systems Biology of Tumor Physiology |
副标题 | Rethinking the Past, |
编辑 | David H. Nguyen |
视频video | |
概述 | Discusses ‘cell origin‘ versus ‘plasticity‘ hypothesis in cancer.Explores how to use mouse models in cancer research.Provides a unique perspective by merging physiology and system biology view of brea |
丛书名称 | SpringerBriefs in Cancer Research |
图书封面 |  |
描述 | This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor microenvironment view. Reductionistic studies of one gene at a time have given way to systems biology approaches that analyze the whole genome (omics) at the same time. However, this text combines the complex levels studying cancer at the molecular biology level, endocrinology level, and transcriptomics level. What researchers are now realizing is that there is a need to combine omics with physiology concepts in order to better understand cancer and this book will give insight to the merging of these two fields in order to define how cancer is studied in the future. |
出版日期 | Book 2016 |
关键词 | cancer stem cell; genetically engineered mice; macrophages; plasticity; tumor microenvironment; Systems B |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-25601-6 |
isbn_softcover | 978-3-319-25599-6 |
isbn_ebook | 978-3-319-25601-6Series ISSN 2194-1173 Series E-ISSN 2194-1181 |
issn_series | 2194-1173 |
copyright | Springer International Publishing Switzerland 2016 |