书目名称 | Systems Biology of Tumor Microenvironment |
副标题 | Quantitative Modelin |
编辑 | Katarzyna A. Rejniak |
视频video | |
概述 | First book devoted entirely to quantitative modeling of tumor microenvironment.Includes examples of integration between math modeling and cancer experiments that can be followed in readers‘ research.G |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be ofinterest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can b |
出版日期 | Book 2016 |
关键词 | tumor microenvironment; mathematical modeling; quantitative biology; tumor-microenvironment interaction |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-42023-3 |
isbn_softcover | 978-3-319-82480-2 |
isbn_ebook | 978-3-319-42023-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |