Titlebook: Systems Biology in Drug Discovery and Development; Methods and Protocol Qing Yan Book 2010 Springer Science+Business Media, LLC 2010 Diseas

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1064-3745 covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, 978-1-4939-5770-5978-1-60761-800-3Series ISSN 1064-3745 Series E-ISSN 1940-6029

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Proteomics and Systems Biology: Application in Drug Discovery and Developments based on their efficacy and safety. Toxicoproteomics is playing an important role in that respect. In essence, over the past decade, proteomics has played a major role in drug discovery and development. In this review article, we explain systems biology, discuss the current proteomic technologies,

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Immunoinformatics and Systems Biology Methods for Personalized Medicineenetic diversity of the immune system may help define patient subgroups for individualized vaccine or drug development. Cellular pathways and host immune-pathogen interactions have a crucial impact on disease pathogenesis and immunogen design. Epigenetic studies may help understand how environmental

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Cancer Systems Biology be effective; instead, different computational and mathematical approaches should be tailored to different types of data, and to each other, in order to test and re-test hypotheses. In time, these models might converge and result in usable tractable models which accurately represent human cancer. L

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Systems Biology of Influenza: Understanding Multidimensional Interactions for Personalized Preventioiviral therapies. The elucidation of host–influenza interactions may provide an integrative view of virus infection and host responses. Understanding the host–influenza–drug interactions may contribute to optimal drug combination therapies. Insight of the host–influenza–vaccine interactions, especia

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Methods in Systems Biology of Experimental Methamphetamine Drug Abusegulated post acute METH treatment. In this chapter, we describe the current protocols for the neuronal cell culture in vitro and the in vivo rat model of acute METH treatment (4 × 10 mg/kg) coupled with the description current bioinformatics analysis utilized to analyze the different implicated inte

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