Titlebook: Systems Biology in Cancer Research and Drug Discovery; Asfar S. Azmi Book 2012 Springer Science+Business Media Dordrecht 2012 Anti-Cancer

Custodian

FOLLY

Applications of Network Bioinformatics to Cancer Angiogenesisy diseases including cancer, age-related macular degeneration, ischemic heart, brain, and skeletal muscle diseases. In this book chapter, we focus on the biological networks associated with angiogenesis in cancer. We review diverse studies on angiogenesis networks, including angiogenic signaling and

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逃避系列单词

Novel and Alternative Bioinformatics Approaches to Understand miRNA-mRNA Interactome in Cancer Reseanslational repression. This intricate interplay between miRNAs and mRNA plays significant roles in complex diseases such as cancer. In this review we will introduce the role of several miRNAs known to be associated with different human cancers. More importantly, we will outline many existing computa

Folklore

Prioritizing Candidate Disease miRNAs by Topological Features in the miRNA-Target Dysregulated Netwoding to the assumption that miRNAs implicated in a specific tumor phenotype will show aberrant regulation of their target genes, we introduce an approach based on the miRNA-target dysregulated network (MTDN) to prioritize novel disease miRNAs. The MTDN is constructed by combining computational targe

通情达理

Development and Clinical Implementation of Reverse Phase Protein Microarrays for Protein Network Actl level. However, since genomic and transcript profiling likely cannot alone sufficiently predict protein pathway activation in each patient’s tumor, and it is these signaling pathways that represent the targets for new molecular guided therapeutics. Thus, it is critical that we begin to define huma