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Titlebook: Systems Biology; International Resear MARVIN CASSMAN,ADAM ARKIN,CYNTHIA STOKES Book 2007 Springer Science+Business Media B.V. 2007 Biologic

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书目名称Systems Biology
副标题International Resear
编辑MARVIN CASSMAN,ADAM ARKIN,CYNTHIA STOKES
视频video
概述Describes the explosively growing, active field of systems biology.A variety of approaches, including software development and simulation of software are discussed
图书封面Titlebook: Systems Biology; International Resear MARVIN CASSMAN,ADAM ARKIN,CYNTHIA STOKES Book 2007 Springer Science+Business Media B.V. 2007 Biologic
描述.Systems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. This involves a variety of approaches, such as the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close linkage with experiment. All of these are discussed in this volume. Of course, the definition becomes ambiguous at the margins, but at the core is the focus on networks, which makes it clear that the goal is to understand the operation of the systems, rather than the component parts....It was concluded that the U.S. is currently ahead of the rest of the world in systems biology, largely because of earlier investment by funding organizations and research institutions. This is reflected in a large number of active research groups, and educational programs, and a diverse and growing funding base. However, there is evidence of rapid development outside the U.S., much of it begun in the last two
出版日期Book 2007
关键词Biological processes; International Research; behavior; biology; databases; development; mathematical mode
版次1
doihttps://doi.org/10.1007/978-1-4020-5468-6
isbn_softcover978-90-481-7375-4
isbn_ebook978-1-4020-5468-6
copyrightSpringer Science+Business Media B.V. 2007
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Modeling and Network Organization,l modeling is the work of Hodgkin and Huxley in 1952 describing how sodium and potassium ion channels could function together to produce the membrane action potential in neurons (Hodgkin and Huxley, 1952). For several decades, models and theory were mostly the domain of applied mathematicians, physi
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Education, National Programs, and Infrastructure in Systems Biology,tical training; the availability of funding that operates outside of disciplinary boundaries; and the availability of a supportive infrastructure that can accommodate the needs of an intrinsically interdisciplinary research area. This chapter will consider the status of these issues both in the U.S.
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Modeling and Network Organization, With the broad availability of computers and IT infrastructure that has emerged in the last several decades, the use of modeling and theory in biological research has expanded greatly, as has the size of the models being developed.
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software are discussed.Systems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. This involves a variety of approaches,
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