书目名称 | Systems Analysis of Human Multigene Disorders |
编辑 | Natalia Maltsev,Andrey Rzhetsky,T. Conrad Gilliam |
视频video | |
概述 | High-throughput experimental genomics technologies for data collection.Bioinformatics approaches for systems-level analysis of biological systems and prediction of causative multidimensional patterns |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance. |
出版日期 | Book 2014 |
关键词 | Systems Biology |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4614-8778-4 |
isbn_softcover | 978-1-4939-5194-9 |
isbn_ebook | 978-1-4614-8778-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |