Titlebook: Synthetic Biology of Yeasts; Tools and Applicatio Farshad Darvishi Harzevili Book 2022 The Editor(s) (if applicable) and The Author(s), und

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Yeast Synthetic Biology for Production of Artemisinin as an Antimalarial Druglectively termed artemisinins) demonstrate additional anticancer, anti-inflammation, antiviral, and anti-SARS-CoV-2 activity. Because of the expensive medicine of artemisinins and the low content of artemisinin biosynthesis in native host, researchers have been endeavored to produce artemisinin via

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Yeast Synthetic Biology for the Production of Terpenoids Derived from Traditional Chinese Medicinal entify active natural products that functioned during disease treatment. Among them, terpenoids are one of the largest natural bioactive products in traditional Chinese medicine. Traditionally, these active terpenoids are extracted from traditional Chinese medicinal plants whose yield of the active

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Synthesis of Polyols and Organic Acids by Wild-Type and Metabolically Engineered , Strainsugh these metabolites have numerous applications in agro-food, chemical, and pharmaceutical industries, the main challenge is to gain productivity to obtain processes that are economically viable. . is known for its ability to use industrial wastes or raw materials as feedstock and to grow at high c

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Recent Advances in Synthetic Biology Applications of , Speciesies. . and . are the two representative . species, which possess uniquely desired biochemical, metabolic, and physiological features favoring large-scale industrial production. This review begins with illustrating synthetic biology parts and tools that have been developed for manipulating these two

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as a Platform in Synthetic Biology for the Production of Useful Materialsng and transcriptome analysis have provided valuable information on its physiological and metabolic characteristics including its capacity for assimilation of various sugars and tolerance to high temperatures, which are distinct from .. These prominent properties enable the development of high-tempe

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Synthetic Biology in the , (CTG) CladeUG-serine coding clade successfully mastered the production of various nutraceutical, commercial, and pharmaceutical valuable compounds. The following chapter aims to snapshot the . CTG clade’s bioengineering properties and their biotechnological applications in synthetic biology.

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Rational Metabolic Pathway Prediction and Design: Computational Tools and Their Applications for Yeaerent strategies for pathway optimization in yeast, namely redox cofactor balancing, improved precursor supply, and heterologous expression of carbon fixation pathways. Finally, challenges and limitations hindering the broad adoption and implementation of these tools for metabolic engineering will be discussed.

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Synthesis of Polyols and Organic Acids by Wild-Type and Metabolically Engineered , Strainsell density in large-scale bioreactor. Recent advances in metabolic engineering and synthetic biology allowed the development of efficient .-based cell factories to bioconvert these feedstocks into added-value metabolites. This book chapter will focus on current knowledge on the synthesis of the most important polyols and organic acids in ..

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Recent Advances in Synthetic Biology Applications of , Speciesspecies, followed by summarizing their applications in biomanufacturing as hosts to produce recombinant proteins, bulk chemicals, and natural products, and concludes on the challenges and potential strategies for advancing them for broader biotechnological applications.