Titlebook: Synaptic Tagging and Capture; From Synapses to Beh Sreedharan Sajikumar,Ted Abel Book 2024Latest edition The Editor(s) (if applicable) and

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Molecular Mechanisms Underlying Synaptic Tagging and Consolidation,specifically enriched at potentiated synapses without requiring new protein synthesis and persist for at least 1 h. Additionally, the intrinsic binding capacity of F-actin and CaMKII is ideal for capturing newly synthesized proteins at the synapse, thereby consolidating the synaptic structure and fu

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Metaplasticity and Synaptic Tag and Capture: Differential Dynamics of Plasticity Regulation in the c plasticity is centrally regulated by protein synthesis such that prior neural activity facilitates the longevity of LTP and LTD, either heterosynaptically or heterodendritically. Although on the surface, both mechanisms appear similar in their ability to confer cell-wide regulation of synaptic pla

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PKA Anchoring and Synaptic Tagging and Capture,ucts? 3. What are the gene products and how are they produced? Although several molecules and processes have been suggested to answer these questions, they only provide partial explanations about the phenomenon. Here, this chapter will discuss how PKA modulates synapse-specific neuronal activity by

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From Where? Synaptic Tagging Allows the Nucleus Not to Care, detect information on how the neuron fits into the network (counting the number of modified or active synapses, or whether inhibitory neurons have a say, for example). We propose that it is the output of the nucleus, or nucleus to synapse signaling, along with the type of synaptic tag formed, that

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Unlocking the Memory Vault: Dopamine, Novelty, and Memory Consolidation in the Hippocampus,h special emphasis on the emerging role of the locus coeruleus (LC) in novelty-associated dopamine-dependent memory consolidation. Furthermore, two distinct dopaminergic systems are explored (the ventral tegmental area (VTA)-hippocampal and LC-hippocampal systems), and the specialization mechanisms