Titlebook: Surgical Oncology Manual; Frances C. Wright,Jaime M. Escallon,Usmaan Hameed Book 2020Latest edition Springer Nature Switzerland AG 2020 Br

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Gastrointestinal Stromal Tumor,nt, and occurrence of intraoperative tumor rupture. The development and ongoing refinement of tyrosine kinase inhibitor (TKI) therapy has led to improvements in the long-term oncologic outcome not only of patients who present with metastatic disease but also of those who present with localized primary tumor.

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Merkel Cell Carcinoma,gement involves surgical excision and consideration of adjuvant radiation therapy for local-regional disease. Systemic therapies for distant metastatic merkel have dramatically improved with immune checkpoint blockade with anti-PD-1 and PDL-1 monoclonal antibodies.

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Non-melanoma Skin Cancer,in cancers as they have a higher metastatic potential (~5% at 5 years). There are a variety of treatment options for both BCC and SCC including surgical excision, Mohs micrographic surgery, topical therapy, local destructive techniques, and radiation therapy.

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Ampullary Cancer, and represent roughly ~7% of periampullary neoplasms. Ampullary carcinoma carries a more favorable prognosis than other pancreaticobiliary malignancies. Surgical resection remains the mainstay of therapy for resectable ampullary carcinoma. Curative-intent resection is possible in ~50% of patients p