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Titlebook: Substance Use Disorders; From Etiology to Tre Michael A. Nader,Yasmin L. Hurd Book 2020 Springer Nature Switzerland AG 2020 Substance Use D

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发表于 2025-3-21 16:28:42 | 显示全部楼层 |阅读模式
书目名称Substance Use Disorders
副标题From Etiology to Tre
编辑Michael A. Nader,Yasmin L. Hurd
视频video
概述Focuses on each substance used and abused from epidemiology, molecular biology, animal models and human subjects/clinical research reinforcing basic principles of pharmacology throughout.Broadens unde
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Substance Use Disorders; From Etiology to Tre Michael A. Nader,Yasmin L. Hurd Book 2020 Springer Nature Switzerland AG 2020 Substance Use D
描述The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees..
出版日期Book 2020
关键词Substance Use Disorders; Preclinical Research; Animal Models; Clinical Trials; Pharmacology; Molecular Bi
版次1
doihttps://doi.org/10.1007/978-3-030-33679-0
isbn_softcover978-3-030-33681-3
isbn_ebook978-3-030-33679-0Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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Translational Molecular Approaches in Substance Abuse Research,anslational research strategies that are applied in the pursuit of new and more effective therapeutics for substance use disorder (SUD). The complex, multidimensional nature of psychiatric disorders like SUD presents difficult challenges to investigators. While animal models are critical for outlini
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Small Molecule Neuropeptide S and Melanocortin 4 Receptor Ligands as Potential Treatments for Subst (SUDs) to date have been mostly ineffective other than substitution-like therapeutics. Two such targets are the peptide G-protein-coupled receptors neuropeptide S (NPS) and melanocortin 4 (MC4). Preclinical evidence suggests that antagonists, inverse agonists, or negative allosteric modulators of t
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Emerging Insights into Mu Opioid Pharmacology,ug development efforts for over a 100 years have resulted in a large variety of opioid analgesics used in the clinic, but all of them continue to exhibit the side effects, especially respiratory depression, that have long plagued the use of morphine. The recent explosion in fatalities resulting from
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Behavioral Pharmacology of Drugs Acting at Mu Opioid Receptors,e detrimental to individuals as well as society and have contributed to the ongoing opioid crisis. The dramatic escalation in overdose deaths over the last 15 years was initially driven by abuse of prescription opioids, although abuse of heroin, fentanyl, and fentanyl analogs has been increasing, la
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Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder,nt learning processes which develop after repeated exposure to drugs of abuse. At the core of this phenotype is the persistence of symptoms, such as craving and relapse to drug seeking, long after the cessation of drug use. The neural basis of these behavioral changes has been linked to dysfunction
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Molecular Mechanisms of Amphetamines,ing these effects are contained within the amphetamine structure. In the first part of this review, the interaction of amphetamine with the dopamine transporter (DAT), crucially involved in its behavioral effects, is covered, as well as the role of dopamine synthesis, the vesicular monoamine transpo
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