Titlebook: Studies on Psychiatric Disorders; Anna Dietrich-Muszalska,Ved Chauhan,Sylvain Grigno Book 2015 Springer Science+Business Media New York 20

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The Reciprocal Effects of Oxidative Stress and Glutamate Neurotransmissionis still the focus of active research. The present section will provide a brief overview of key components of glutamatergic transmission. The impact of redox status on glutamate release, reuptake, receptor expression, and function will be reviewed as well as some aspects of the complex neuroenergeti

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Mitochondrial Dysfunction in Psychiatric Disorders is particularly interesting as it can manifest a wide variety of symptoms including abnormalities in central nervous system functioning with focal neurological, cognitive, behavioral, and psychiatric symptoms. Evidence has started to accumulate that mitochondrial dysfunction plays a role in schizop

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The Kynurenine Pathway at the Interface Between Neuroinflammation, Oxidative Stress, and Neurochemichas been intensively explored. Recently, it has been postulated that KP could play a major role in both brain physiology and pathology, and this is due to the fact that this metabolic pathway contains at least two well-characterized neuroactive metabolites: quinolinic acid and kynurenic acid (KYNA).

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The Role of Nitric Oxide and Nitrosative Stress in Schizophreniaogenesis of schizophrenia. Effects of NO on dopamine release in the striatum and prefrontal cortex have been reported indicating that NO is an important modulator of dopaminergic activity. Further, NO seems to be involved in attentional deficits produced by dopamine hyperfunction. Polymorphisms of N

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Dysregulation of Glutathione Synthesis in Psychiatric Disorderscal, and biochemical consequences of GSH deficiency in animal models. Finally, a treatment restoring the redox balance, especially application of N-acetylcysteine, in the therapy of schizophrenia and bipolar disorder is also discussed.

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Book 2015isorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeutic aspects. Together, these chapters present the envi