Titlebook: Studies in Diabetes; Irina Obrosova,Martin J. Stevens,Mark A. Yorek Book 2014 Springer Science+Business Media New York 2014 Diabetes.Oxida

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Oxidative Stress and Diabetes-Induced Vascular Dysfunction: Role in Diabetic Neuropathy, Oxidative stress occurs when the balance between the production of oxidation products and the ability of antioxidant mechanisms to neutralize these products is tilted in the favor of the former. The production of reactive oxygen species has been shown to be increased in patients with diabetes. The

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Complications in the Coronary Circulation Associated with Diabetes,and endothelial dysfunction. In the coronary microcirculation, endothelial dysfunction causes chronic vasodilation that leads to increased capillary pressure and hyperperfusion, which in turn leads to morphologic changes that narrow the lumen, and limits the ability of the diabetic coronary circulat

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Optimal Measures of Small Fiber Neuropathy in Diabetic Polyneuropathy,o the genesis of foot ulceration via reduced heat and pain perception, sudomotor dysfunction, and blunted pressure-induced vasodilation. Small fiber damage may also precede large fiber damage in subjects with impaired glucose tolerance (IGT) and early diabetic neuropathy. A number of functional test

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Oxidative Stress and Complications of the Diabetic Foot,omplications of the lower limb in diabetes lies in prevention through the implementation of screening programs aimed at the early detection of neuropathy, ischemia, deformity, and edema. However, even with aggressive screening, chronic ulceration of the lower limbs remains one of the most common and

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Encephalopathies Accompanying Type 1 and Type 2 Diabetes, to their clinical pictures and underlying pathogenetic mechanisms. The encephalopathy accompanying type 1 diabetes affects learning abilities, intelligence development, and memory retrieval with adverse effects on school performances. The major underlying culprit appears to be insulin and C-peptide

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Oxidative Stress, Inflammation and Endothelial Dysfunction: The Link Between Obstructive Sleep Apnoding to the activation of poly(ADP-ribose) polymerase, inflammation and endothelial dysfunction play an important role in the development of vascular disease in patients with diabetes. Obstructive sleep apnoea (OSA) is very common in patients with type 2 diabetes and is associated with increased ris