Titlebook: Structure-Based Mechanics of Tissues and Organs; Ghassan S. Kassab,Michael S. Sacks Book 2016 Springer Science+Business Media, LLC 2016 Ce

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Modeling of Collagenous Tissues Using Distributed Fiber Orientations,. The objective of this chapter is to describe the methods to analyze the mechanical behavior of tissues with fiber orientation distributions. This chapter includes methods to measure fiber orientation, a detailed description of Lanir’s formulation, simplified versions of Lanir’s approach, and appli

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Histomechanical Modeling of the Wall of Abdominal Aortic Aneurysm,l according to Lanir’s pioneering approach. Consequently, macroscopic properties were derived through an integration of distributed fibers, where collagen was regarded as the most important protein of the aneurysmatic Extra Cellular Matrix (ECM). Collagen organization was quantified through Polarize

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The Biomechanics of Fat: From Tissue to a Cell Scale,a novel hypothesis regarding structure–function–adaptation processes and relationships in fat, which might open new research paths for studying adipose-related diseases from a biomechanical point of view, involving the mechanotransduction and structure–function–adaptation concepts that are well know

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Biomechanical Basis of Myocardium/Vessel Interaction: Implications for Pathophysiology and Therapy,alistic, however, it must incorporate both a realistic description of the coronary network and the manner by which the contracting myocardium affects coronary flow—the myocardium/vessel interaction (MVI). Such an approach has several inherent challenges: First, the vast number of coronary blood vess

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Microstructure-Based Constitutive Models for Coronary Artery Adventitia, a reinforced phase. The model accounts for the waviness, orientation and spatial distributions of collagen fibers and provides a good prediction of macroscopic responses of the tissue which agree well with the finite element simulation results as a golden standard. We then use multiphoton microscop

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Fibers to Organs: How Collagen Fiber Properties Modulate the Closing Behavior of the Mitral Valve, computational model would serve as a logical first step toward our long-term modeling goal—facilitating simulation-guided design of optimal surgical repair strategies for treating diseased MVs with significantly enhanced durability.

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