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Titlebook: Stem Cells in Reproduction and in the Brain; J. Morser,S. -I. Nishikawa,H. R. Schöler Conference proceedings 2006 Springer-Verlag Berlin H

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Toward Reprogramming Cells to Pluripotency,nuclear transfer (therapeutic cloning) may offer this possibility; however, ethical guidelines prevent application of this technology in many in countries. As a result, alternative approaches are being developed for altering cell fate. This communication discusses recent non-nuclear transfer-based i
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Molecular Switches and Developmental Potential of Adult Stem Cells, to a terminally differentiated mature cell type. Hematopoiesis, the development of blood cells from hematopoietic stem cells in bone marrow, is particularly well studied, and at different branching points within the hematopoietic system multiple developmental intermediates have been identified. Her
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Adult Small Intestinal Stem Cells: Identification, Location, Characteristics, and Clinical Applicatefined cell migratory pathways, and dynamic cell replacement is a model tissue providing unique opportunities for stem cell study. Lineage tracking indicates that all cell replacement originates at well-defined stem cell positions, with an associated slower cell cycle. Radiobiological studies sugges
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Establishment of Nuclear Transfer Embryonic Stem Cell Lines from Adult Somatic Cells by Nuclear Trated relatively easily from a variety of mouse genotypes and cell types of both sexes, even though it may be more difficult to generate clones directly. Several reports have already demonstrated that ntESCs can be used in regenerative medicine in order to rescue immunodeficient or infertile phenotype
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Germline Recruitment in Mice: A Genetic Program for Epigenetic Reprogramming, totipotent state. We wish to understand the molecular basis of the unique properties of the mammalian germ line. Recently we identified Blimp1, a potent transcriptional repressor of a histone methyltransferase subfamily, as a critical determinant of the germ cell lineage in mice. Surprisingly, Blim
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