Titlebook: Stem Cells in Cancer: Should We Believe or Not?; Enrique Grande,Luis Antón Aparicio Book 2014 Springer Science+Business Media Dordrecht 20

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Stem Cells in Colon Cancer,ultistep process of oncogenes activation and inactivation of tumor suppressor genes. But the cell of origin and the type of cells that propagate the tumor after its initiation are still unknown..The concept of Cancer Stem Cells (CSC) was first developed for hematologic malignancies and later applied

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Cancer Stem Cells in Genitourinary Cancer,r, are an important focus of attention in this field. Prostate cancer is the second leading cause of cancer death in men after lung cancer, and Cancer Stem Cells have been proposed as one of the mechanisms of resistance to hormonal treatment and chemotherapy. Epithelial to Mesenchimal Transition is

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Stem Cells in Pancreatic Cancer,he efforts in therapy research and those to improve the survival of patients with pancreatic cancer in the last 10 years, there has not been major advance. The increasing study and understanding of pancreatic cancer biology has led us to discover the pancreatic cancer stem cells (CSC), a cell subpop

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Cancer Stem Cells in Gastric Cancer, stem cell (GCSC) investigations are part of the expanding research field of cancer stem-cell biology of a wide variety of organs. New evidence of several years of investigation, indicate the existence of cancer stem cell. Several data suggest that a subpopulation with a defined marker show spheroid

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Cancer Stem Cells in Melanoma,ion, to remain quiescent for long time and to have an innate resistance to chemotherapy and radiotherapy. These features suggest that they are responsible for relapse and metastasis. In melanoma, subsets of tumoral cells with these characteristics have been identified using CSC markers such as ALDH1

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Sarcomagenesis,bly regarding the origin of sarcomas having putative sarcoma stem cells which are responsible for the initiation, maintenance, differentiation and proliferation of osteosarcoma, synovial sarcoma, rhabdomyosarcoma and Ewing’s sarcoma. Different methods have been adopted for identifying primitive cell

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Cancer Stem Cells in Gynecologic Cancer,uman Papilloma Virus, gynecological cancers -mostly ovarian cancer- are often diagnosed at advanced stages. Although the high effectiveness of existing medical treatments, during long term therapy, often seem insufficient to achieve the cure or the disease. This is due to the presence of metastases

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ation.Reviews current research in this field of stem cells a.This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell

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Sarcomagenesis, population analysis. This chapter summarizes and discusses data regarding the tumorigenesis of sarcomas, assessing their potential role in sensitivity and resistance to different classical interventions (chemotherapy and radiotherapy) as well as new molecularly-directed therapies.