书目名称 | Stem Cells in Cancer: Should We Believe or Not? | 编辑 | Enrique Grande,Luis Antón Aparicio | 视频video | | 概述 | Updates the field on stem cells in cancer, providing information on new molecular pathways with new targeted agents currently under investigation.Reviews current research in this field of stem cells a | 图书封面 |  | 描述 | .This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different roles that cancer stem cells seem to have according to the organ they are placed in, and the future role that targeting cancer stem cells may have in the management of patients in the clinic..Exploring the latest research including new data from randomized trials, this book examines important proposals over the origin of cancer stem cells such as the possibility that cancer stem cells may arise from mutated stem cells or a fully differentiated cell that may undergo several mutations that drive it back to a stem-like state. The authors consider the role that stem cells seem to have in the onset, development and resistance to classical antitumoral treatments of cancer and discuss possible potential future treatment modalities for the management of advanced cancer patients..The question, "Are stem cells involved in cancer?" may not have a simple answer, but ongoing investigations, in-depth | 出版日期 | Book 2014 | 关键词 | Hedgehog; Notch; Wnt; cancer biology; cancer stem cells | 版次 | 1 | doi | https://doi.org/10.1007/978-94-017-8754-3 | isbn_softcover | 978-94-024-0323-7 | isbn_ebook | 978-94-017-8754-3 | copyright | Springer Science+Business Media Dordrecht 2014 |
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