Titlebook: Stem Cells from Cord Blood, in Utero Stem Cell Development and Transplantation-Inclusive Gene Therap; W. Holzgreve,M. Lessl Conference pro

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Legal and Ethical Issues Involved in Cord Blood Transplantation and Banking,nity. The debate on euthanasia has redefined the position of human life in the hierarchy of values. Towards the provisional end of the debate in Germany, questions of legal autonomy and legally protected reverence appear in a new light.

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Origin and Developmental Plasticity of Haematopoietic Stem Cells,ained by a hierarchical structured cell system, with stem cells as their cellular origin. Stem cells are functionally defined by their capacity to self-renew and to lead to multi-lineage differentiation; hence, stem cells have the ability to generate both new stem cells and to clonally regenerate al

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,The New York Blood Center’s Placental/Umbilical Cord Blood Program. Experience with a ‘New’ Source (PCB) was made in 1988 by Boyse, Gluckman and their colleagues. Gluckman’s transplant (Gluckman et al. 1989) was the culmination of much work during the two preceding decades that showed the presence of colony-forming progenitor cells and others capable of at least some self-replication in human PCB

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Prenatal Transplantation of Hematopoietic Stem Cells: Overview, contrast to prenatal diagnosis, prenatal therapy has shown limited success so far. Therefore, if a severe congenital disease is diagnosed early in gestation, many parents choose to terminate pregnancy. Prenatal transfer of hematopoietic stem cells (HSC) is a promising approach to successfully treat

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Fetal Hematopoietic Stem Cells: In Vitro Expansion and Transduction Using Lentiviral Vectors,lood, the content of CD34. and CD34.CD38. cells in CB is approximately tenfold higher and thus comparable to adult bone marrow (Broxmeyer et al. 1989, 1990; Hao et al. 1995). Moreover, CB progenitors have high plating efficiency in clonogenic assays, they respond rapidly to cytokine stimulation in v